What Is Cellular Metabolism?
(DrEddyClinic News) Your body is a complex network of interconnected organs that perform individual functions to support the systems and processes that make up your existence. Respiration, digestion, bone regeneration, metabolism — they’re all examples of your body’s ability to function with machine-like precision. That functionality exists at the most basic level as well— your cellular level. Lungs, brain, stomach, bones, blood — everything — is comprised of cells. Cells are the microscopic components that make up organisms and they, like your body, are a collection of various components that work together to perform the processes that sustain life.
The collection of chemical reactions in your body is usually referred to as your metabolism. This process is the sum of all chemical changes that take place within the cells in your body. During digestion, for example, cellular metabolism is what releases energy from nutrients. Cellular metabolism sustains life and allows cells to grow, develop, repair damage, and respond to environmental changes.
Cellular metabolism can break down organic matter, which is referred to as catabolism. Cellular metabolism can also produce substances, a process referred to as anabolism. To provide a more graspable example, breaking down food so the nutrients can be utilized is a catabolic reaction. The production of proteins from amino acids is an example of an anabolic reaction.
Metabolism is usually divided into two categories: catabolism, the breaking down of organic matter, for example, by cellular respiration, and anabolism, the assembly of components of cells such as proteins and nucleic acids. Usually, breaking down releases energy and building up consumes energy.
Most of the structures that make up animals, plants, and microbes are made from three basic types of molecules: amino acids, carbohydrates, and lipids (often called fats http://www.dreddyclinic.com/forum/viewtopic.php?f=18&t=36204). As these molecules are vital for life, metabolic reactions either focus on making these molecules during the construction of cells and tissue or digesting them and using them as a source of energy.
There are two kinds of cellular reactions: catabolic and anabolic.
Catabolic Cellular Metabolism
Catabolic metabolism breaks down complex organic molecules into more simple molecules. These exergonic reactions are characterized by the release of energy. Catabolism reduces protein, fat, and carbohydrates into amino acids, fatty acids, and simple sugars, respectively. The energy released from catabolic reactions drives anabolic reactions. It’s a process that has three stages:
1. Breakdown of complex molecules into their basic building blocks.
2. Breakdown of the basic building blocks into even more simple metabolic intermediates.
3. “Combustion” of the acetyl groups of acetyl-coenzymeA by the citric acid cycle and oxidative phosphorylation to produce CO2 and H2O. In other words, energy is released.
Anabolic Cellular Metabolism
Whereas catabolic metabolism breaks down molecules into their constituents, anabolic metabolism combines simple substances into more complex substances. When your cells combine amino acids into proteins to produce cells or tissues, that’s anabolism. Anabolic reactions are endergonic reactions, which means they use more energy than they produce.
Although catabolism and anabolism occur independently of each other, they are inextricably linked. Energy produced by catabolic reactions provides energy for anabolic reactions. Without cellular metabolism, the body’s cells wouldn’t be able to break down or synthesize the compounds needed for energy, growth, function, and healing.
The Role of Cells
Your body is comprised of an incalculable number of cells, and many different types of cells at that. Brain cells are different from blood cells, which are different from bone cells, which are different from skin cells, and so on. Every cell in your body is uniquely suited for a specific purpose. Some cells store fat reserves. Others send electrochemical messages to the brain.[8,9] Different cells have different features and may even have structural differences depending on their purposes.
Although cell structure may vary from one to the next, all cells share several basic traits. Organelles are one feature that all cells possess. Organelles are like miniature organs within the cell that perform different specialized functions. For example, mitochondria are a type of organelle responsible for releasing energy. Other examples include the cell nucleus and endoplasmic reticulum.
Diagram of an animal cell with a description of the organelles within the cell.
Encircles the cytoplasm and organelles of the cell and regulates what substances enter and exit the cell.[11, 12]
The jelly-like fluid that surrounds the nucleus and holds the organelles in suspension.
A network of long fibers that comprise the cell’s structural framework. The cytoskeleton also acts like a rail system and helps organelles move to where they are needed.
The endoplasmic reticulum (ER) is a folded maze of flattened sacs which envelops the nucleus. Although the primary function of the ER is to produce important proteins and fats that are used in a variety of ways, the ER actually has two components — the smooth ER and the rough ER. The rough ER assembles proteins. The smooth ER is responsible for detoxifying the cell of waste products and toxins, producing fats, and other important functions.
Accepts vesicles, of packages of cell-generated products, from the ER and repacks them to be sent outside the cell. It also is responsible for creating lysosomes.
Lysosomes and Peroxisomes
Lysosomes and peroxisomes are the recycling centers of the cell, refashioning the old, worn-out components.
Mitochondria are the powerhouses of the cell and when they’re functioning normally, they convert nutrients into energy the body needs to survive. When mitochondria fail, however, energy production is impaired and that can affect any number of important processes within the cell and the body as a whole. Inefficient mitochondria may be due to poor nourishment, genetics, environmental toxins, or disease.
Nestled within the folds of the ER is the nucleus. This organelle is the cell’s command center and contains DNA, including the noncoding telomeres that protect our chromosomes http://dreddyclinic.com/forum/viewtopic.php?f=113&t=34007. The cell will grow, mature, divide or die based on the instructions it receives from the nucleus.
Ribosomes interpret DNA information and create proteins.
How to Support Cellular Function
Cellular function directly affects how you feel. If your body is operating poorly at the cellular level, it’s a sure bet your well-being will be affected.
Supporting cellular function in your body really is a “garbage in, garbage out” proposition. If your diet isn’t balanced and a complete source of all the essential nutrients your body requires, then your cells aren’t being given the fuel they need. If your nutrient intake is incomplete or inconsistent, consider organic supplements to help fill the gaps.
Vitamin B-12 http://www.dreddyclinic.com/forum/viewtopic.php?f=21&t=33583, in particular, is a nutrient that plays a very important role in supporting energy levels and metabolic function. Many people don’t get enough vitamin B-12 and, as a result, their energy levels suffer. If you feel chronically fatigued, you may benefit from incorporating a B-12 supplement in your diet .
Vitamin D http://www.dreddyclinic.com/forum/viewtopic.php?f=33&t=33211 also supports normal cellular function. It’s difficult to get enough vitamin D in your diet but with adequate skin exposure to sunlight (UVB rays), your body will produce vitamin D. Regular exercise can boost your health and well-being in many ways; improving cellular function is one of them. It’s also important to stay hydrated and consume plenty of clean, purified water http://www.dreddyclinic.com/forum/viewtopic.php?f=11&t=33851. Hydrated cells are better able to repair and rebuild bones, regenerate and replace tissue, and defend against harmful organisms.
For extra support, we’ve formulated Cell Fuzion™ http://www.dreddyclinic.com/forum/viewtopic.php?f=113&t=30718. It’s a dietary supplement designed to protect the mitochondria, facilitate cellular metabolism, sustain healthy cell cycles, and guard against DNA damage. Cell Fuzion contains some of the strongest antioxidants available and one of its ingredients, CoQ10, may protect DNA by supporting telomere structure. Supporting telomere integrity is one of the best ways to defend against the cellular aging that weakens cell metabolism.
If you’re interested in more tips and information for healthy living, check out the Secret To Health http://www.dreddyclinic.com/forum/viewtopic.php?f=11&t=33524. Filmed live in Houston, it’s my presentation on how to live a clean, green, healthy life. It covers strategies for avoiding environmental toxins and offers practical advice for taking control of and maximizing your health and wellness.
Do you have any tips for staying well? Leave a comment below and share your thoughts.
by Dr. Edward Group DC, NP, DACBN, DCBCN, DABFM
1. “Cellular Respiration: Or, How one good meal provides energy for the work of 75 trillion cells http://www.biology.iupui.edu/biocourses/N100/2k4ch7respirationnotes.html.” IUPUI Dept. of Biology. 16 Feb. 2004. Web. 19 Aug. 2016.
2. “Cellular Respiration http://hyperphysics.phy-astr.gsu.edu/hbase/biology/celres.html.” Gsu.edu. n.d. Web. 19 Aug. 2016.
3. Pearson Education, Inc. Mossmanc Chapter 23 http://www.foothill.edu/attach/1578/mossman30bchpt_23.pdf. N.p.: Pearson Education, 2010. Web. 19 Aug. 2016.
4. “Chemistry for Biologists: Metabolism and energy http://www.rsc.org/Education/Teachers/Resources/cfb/metabolism.htm.” RSC | Advancing the Chemical Sciences. n.d. Web. 19 Aug. 2016.
5. “Cellular Respiration http://www.cod.edu/people/faculty/fancher/Bio101/CellularRespiration.doc.” COD.edu. n.d. PDF. 19 Aug. 2016.
6. “Rate of Exergonic Reactions http://academic.brooklyn.cuny.edu/biology/bio4fv/page/exergon.htm.” City University of New York. n.d. Web. 19 Aug. 2016.
7. “Differentiation and Lineage Commitment of Adipocytes and Energy Metabolism https://www.hsph.harvard.edu/gsh-lab/research/differentiation-and-lineage-commitment-of-adipocytes-and-energy-metabolism/.” Harvard School of Public Health. 2016. Web. 19 Aug. 2016.
8. “Introduction to Neurons and Neuronal Networks http://neuroscience.uth.tmc.edu/s1/introduction.html.” Department of Neurobiology and anatomy – the university of Texas medical school at Houston. 1997. Web. 19 Aug. 2016.
9. “The Neuron http://users.ipfw.edu/abbott/120/neuron.html.” Indiana University | Purdue University. n.d. Web. 19 Aug. 2016.
10. HULL, DAVID. “THE STRUCTURE AND FUNCTION OF BROWN ADIPOSE TISSUE http://bmb.oxfordjournals.org/content/22/1/92.extract.” British Medical Bulletin 22.1 (1966): 92–96. Web. 19 Aug. 2016.
11. Spector, Arthur A, and Mark A Yorek. Membrane Lipid Composition http://www.jlr.org/content/26/9/1015.full.pdf. 2002. Web. 19 Aug. 2016.
12. “SEER Training: Cell Function http://training.seer.cancer.gov/anatomy/cells_tissues_membranes/cells/function.html.” National Institute of Health, National Cancer Institute, SEER Training Modules. n.d. Web. 19 Aug. 2016.
13. “What is a cell? https://ghr.nlm.nih.gov/primer/basics/cell” NIH Genetics Home Reference. Genetics Home Reference, 16 Aug. 2016. Web. 19 Aug. 2016.
14. “Molecular Expressions Cell Biology: Endoplasmic Reticulum https://micro.magnet.fsu.edu/cells/endoplasmicreticulum/endoplasmicreticulum.html.” Florida State University. 1995. Web. 19 Aug. 2016.
15. “Golgi Apparatus http://hyperphysics.phy-astr.gsu.edu/hbase/biology/golgi.html.” Georgia State University. n.d. Web. 19 Aug. 2016.
16. Cooper, Geoffrey M. Lysosomes http://www.ncbi.nlm.nih.gov/books/NBK9953/. N.p.: Sinauer Associates, 2000. Web. 19 Aug. 2016.
17. “Mitochondrial DNA Analysis http://www.uvm.edu/~biology/Classes/296D/10_Mitochondria.pdf.” 2007. Web. 19 Aug. 2016.
18. “Office of Dietary Supplements – Dietary Supplement Fact Sheet: Vitamin B12 https://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/.” NIH. 11 Feb. 2016. Web. 19 Aug. 2016.
19. Harinarayan CV, Arvind S, Joshi S, Thennarasu K, Vedavyas V, Baindur A. IMPROVEMENT IN PANCREATIC β-CELL FUNCTION WITH VITAMIN D AND CALCIUM SUPPLEMENTATION IN VITAMIN D-DEFICIENT NONDIABETIC SUBJECTS http://www.ncbi.nlm.nih.gov/pubmed/24014012. Endocr Pract. 2014 Feb;20(2):129-38.
20. Holick MF. Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease http://www.ncbi.nlm.nih.gov/pubmed/15585788. Am J Clin Nutr. 2004 Dec;80(6 Suppl):1678S-88S.
21. “Exercise and immunity https://www.nlm.nih.gov/medlineplus/ency/article/007165.htm.” Medline Plus. Review Date 1/10/2016.
22. Fossel, Michael, Greta Blackburn, and Dave Woynarowski. AARP the Immortality Edge: Realize the Secrets of Your Telomeres for a Longer Healthy Life. N.p.: John Wiley, 2012. eBook. 19 Aug. 2016.